Article
Role of SATB2 in human pancreatic cancer: Implications in transformation and a promising biomarker.
Oncotarget - 6 Sept 2016
Yu Wei, Ma Yiming, Shankar Sharmila, Srivastava Rakesh K
Abstract excerpt
SATB2 (special AT-rich binding protein-2), a transcription factor and chromatin modulator, regulates the expression of genes required for maintaining pluripotency and self-renewal. The molecular mechanisms by which human pancreatic normal ductal epithelial cells are transformed to cancer cells are not well understood. The main goal of the paper is to examine the molecular mechanisms by which SATB2 regulates...
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