Article
Association of tripartite motif family-like 2 (TRIML2) polymorphisms with late-onset Alzheimer's disease risk in a Korean population.
Neuroscience letters - 6 Sept 2016
Kang Won Sub, Park Jin Kyung, Kim Young Jong, Cho Ah Rang, Park Hae Jeong, Kim Su Kang, Paik Jong-Woo, Lee Kang Joon, Na Hae Ri, Kim Young Youl, Lim Hyun Kook, Jeong Hyun-Ghang, Kim Jong Woo
Abstract excerpt
Apoptosis is a prominent feature in the progression of Alzheimer's disease (AD), regulated in part by the activity of p53. As tripartite motif family-like 2 (TRIML2), a member of the TRIM family of proteins, has been implicated in the regulation of p53-mediated apoptosis, we hypothesized that TRIML2 polymorphisms may result in an increased AD susceptibility. Here, we investigated the association between coding...
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