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Genetic analysis of TRIM family genes for early-onset Parkinson's disease in Chinese population.

Parkinsonism & related disorders - 1 Sept 2021

Li ChunYu, Ou RuWei, Hou YanBing, Chen YongPing, Gu XiaoJing, Wei QianQian, Cao Bei, Zhang LingYu, Liu KunCheng, Chen XuePing, Song Wei, Zhao Bi, Wu Ying, Shang HuiFang

Abstract excerpt

INTRODUCTION: Amounting evidence has suggested the Tripartite Motif (TRIM) family proteins as related to Parkinson's disease (PD). However, many of the risk genes were still awaiting further explorations, and their genetic role in PD has not been investigated yet. METHODS: Here, we aimed to systematically evaluate the genetic associations of TRIMs with PD in a large Chinese early-onset PD (EOPD, age at onset < 50...

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PMID: 34419804
DOI: 10.1016/j.parkreldis.2021.08.005

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