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Article

Response to AREDS supplements according to genetic factors: survival analysis approach using the eye as the unit of analysis.

The British journal of ophthalmology - 1 Dec 2016

Seddon Johanna M, Silver Rachel E, Rosner Bernard

Abstract excerpt

BACKGROUND/AIMS: The Age-Related Eye Disease Study (AREDS) reported the beneficial impact of antioxidant and zinc supplements on the risk of progression to advanced stages of age-related macular degeneration (AMD). We evaluated the role of genetic variants in modifying the relationship between supplementation and progression to advanced AMD. METHODS: Among 4124 eyes (2317 subjects with a genetic specimen), 882...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27471039
DOI: 10.1136/bjophthalmol-2016-308624
PMCID: PMC6570490

Genes

CFH
ARMS2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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