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Article

No clinically significant association between CFH and ARMS2 genotypes and response to nutritional supplements: AREDS report number 38.

Ophthalmology - 1 Nov 2014

Chew Emily Y, Klein Michael L, Clemons Traci E, Agrón Elvira, Ratnapriya Rinki, Edwards Albert O, Fritsche Lars G, Swaroop Anand, Abecasis Gonçalo R

Abstract excerpt

OBJECTIVE: To determine whether genotypes at 2 major loci associated with late age-related macular degeneration (AMD), complement factor H (CFH) and age-related maculopathy susceptibility 2 (ARMS2), influence the relative benefits of Age-Related Eye Disease Study (AREDS) supplements. DESIGN: Unplanned retrospective evaluation of a prospective, randomized, placebo-controlled clinical trial of vitamins and minerals...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24974817
DOI: 10.1016/j.ophtha.2014.05.008
PMCID: PMC4253656

Genes

ARMS2
CFH

Variants

rs1061170

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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