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Article

CFH and LOC387715/ARMS2 genotypes and treatment with antioxidants and zinc for age-related macular degeneration.

Ophthalmology - 1 Jun 2008

Klein Michael L, Francis Peter J, Rosner Bernard, Reynolds Robyn, Hamon Sara C, Schultz Dennis W, Ott Jurg, Seddon Johanna M

Abstract excerpt

OBJECTIVE: To determine if CFH and LOC387715/ARMS2 genotypes influence treatment response to AREDS-type nutritional supplementation with antioxidants and zinc. DESIGN: Retrospective analysis of participants in a randomized, controlled clinical trial, the Age-Related Eye Disease Study (AREDS). PARTICIPANTS AND/OR CONTROLS: Eight hundred seventy-six AREDS study participants who were considered at high risk for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18423869
DOI: 10.1016/j.ophtha.2008.01.036

Genes

CFH
ARMS2

Variants

rs1061170
rs1061170

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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