Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Quantification of [ <sup>11</sup> C]Ro15-4513 GABA <sub>A</sub> α5 specific binding and regional selectivity in humans

27 Jul 2016

Abstract excerpt

[ 11 C]Ro15-4513 has been introduced as a positron emission tomography radioligand to image the GABA A α5 receptor subtype thought to be important in learning, memory and addiction. However, the in vivo selectivity of the ligand remains unknown and a full assessment of different analysis approaches has yet to be performed. Using human heterologous competition data, with [ 11 C]Ro15-4513 and the highly selective...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Advanced MRI Techniques and Applications
Share to Medical Imaging Techniques and Applications
Share to Neuroscience and Neuropharmacology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27466376
DOI: 10.1177/0271678x16661339

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Quantification of [ <sup>11</sup> C]Ro15-4513 GABA <sub>A</sub> α5 specific binding and regional selectivity in humansPMID 27466376Read ↗

Cellular and molecular signatures of <i>in vivo</i> GABAergic neurotransmission in the human brainSemantic proximity Read ↗

GABA<sub>A</sub>receptor availability in clinical high-risk and first-episode psychosis: a [<sup>11</sup>C]Ro15-4513 positron emission tomography studySemantic proximity Read ↗

A High-Resolution In Vivo Atlas of the Human Brain’s Benzodiazepine Binding Site of GABA <sub>A</sub> ReceptorsSemantic proximity Read ↗

Fenfluramine evokes 5‐HT<sub>2A</sub> receptor‐mediated responses but does not displace [<sup>11</sup>C]MDL 100907: Small animal PET and gene expression studiesSemantic proximity Read ↗

<i>in vivo</i> Variation in Metabotropic Glutamate Receptor Subtype 5 Binding Using Positron Emission Tomography and [ <sup>11</sup> C]ABP688Semantic proximity Read ↗

Positron Emission Tomography (PET) Imaging Tracers for Serotonin ReceptorsSemantic proximity Read ↗

A high-resolution in vivo atlas of the human brain's benzodiazepine binding site of GABAA receptorsSemantic proximity Read ↗

PET Imaging of the Serotonin 1A Receptor in Major Depressive Disorder: Hierarchical Multivariate Analysis of [ <sup>11</sup> C]WAY100635 Overcomes Outcome Measure DiscrepanciesSemantic proximity Read ↗

Kinetic Analysis and Quantification of [<sup>11</sup>C]Martinostat for in Vivo HDAC Imaging of the BrainSemantic proximity Read ↗

Longitudinal Comparative Quantification of [18F]RO948 and florzolotau (18F) PET in the TgF344-AD Rat Model.Semantic proximity Read ↗

Identification and characterization of potent and selective inhibitors for the B <sup>0</sup> AT2/SLC6A15 amino acid transporterSemantic proximity Read ↗

A Database of [11C]WAY-100635 Binding to 5-HT1A Receptors in Normal Male Volunteers: Normative Data and Relationship to Methodological, Demographic, Physiological, and Behavioral VariablesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.