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Positron Emission Tomography (PET) Imaging Tracers for Serotonin Receptors

8 Aug 2022

Abstract excerpt

Serotonin (5-hydroxytryptamine, 5-HT) and 5-HT receptors (5-HTRs) have crucial roles in various neuropsychiatric disorders and neurodegenerative diseases, making them attractive diagnostic and therapeutic targets. Positron emission tomography (PET) is a noninvasive nuclear molecular imaging technique and is an essential tool in clinical diagnosis and drug discovery. In this context, numerous PET ligands have been...

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PMID: 35939391
DOI: 10.1021/acs.jmedchem.2c00633

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