Article
Serum gamma-glutamyl transferase and risk of type 2 diabetes in the general Korean population: a Mendelian randomization study.
Human molecular genetics - 1 Sept 2016
Lee Youn Sue, Cho Yoonsu, Burgess Stephen, Davey Smith George, Relton Caroline L, Shin So-Youn, Shin Min-Jeong
Abstract excerpt
Elevated gamma-glutamyl transferase (GGT) levels are associated with higher risk of type 2 diabetes in observational studies, but the underlying causal relationship is still unclear. Here, we tested a hypothesis that GGT levels have a causal effect on type 2 diabetes risk using Mendelian randomization. Data were collected from 7640 participants in a South Korean population. In a single instrumental variable (IV)...
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