Alcohol Use and Gamma-Glutamyltransferase Using a Mendelian Randomization Design in the Guangzhou Biobank Cohort Study.

doi:10.1371/journal.pone.0137790

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Alcohol Use and Gamma-Glutamyltransferase Using a Mendelian Randomization Design in the Guangzhou Biobank Cohort Study.

PloS one - 1 Jan 2015

Xu Lin, Jiang Chao Qiang, Cheng Kar Keung, Au Yeung Shiu Lun Ryan, Zhang Wei Sen, Lam Tai Hing, Schooling Catherine Mary

Abstract excerpt

BACKGROUND: Observational studies and small intervention studies suggest alcohol raises gamma-glutamyltransferase (GGT). We used Mendelian randomization to assess the causal effect of alcohol use on GGT in older Chinese people. METHODS: An instrumental variable (IV) analysis in 2,321 men and 2,757 women aged 50+ years from phase 3 of the Guangzhou Biobank Cohort Study with ALDH2 (rs671) genotyped, alcohol use and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcohol Drinking

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aldehyde Dehydrogenase

Share to Aldehyde Dehydrogenase, Mitochondrial

Share to China

Share to Cohort Studies

Share to gamma-Glutamyltransferase

Share to Mendelian Randomization Analysis

Share to Socioeconomic Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 26356841
DOI: 10.1371/journal.pone.0137790
PMCID: PMC4565586

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alcohol Use and Gamma-Glutamyltransferase Using a Mendelian Randomization Design in the Guangzhou Biobank Cohort Study.PMID 26356841Read ↗

Is aldehyde dehydrogenase 2 a credible genetic instrument for alcohol use in Mendelian randomization analysis in Southern Chinese men?Semantic proximity Read ↗

Molecular Alterations Caused by Alcohol Consumption: A Mendelian Randomisation StudySemantic proximity Read ↗

Evaluation of moderate alcohol use and cognitive function among men using a Mendelian randomization design in the Guangzhou biobank cohort study.Semantic proximity Read ↗

Causal effect of alcohol consumption on hyperuricemia using a Mendelian randomization designSemantic proximity Read ↗

Evaluation of Moderate Alcohol Use With QT Interval and Heart Rate Using Mendelian Randomization Analysis Among Older Southern Chinese Men in the Guangzhou Biobank Cohort Study.Semantic proximity Read ↗

Serum gamma-glutamyl transferase and risk of type 2 diabetes in the general Korean population: a Mendelian randomization study.Semantic proximity Read ↗

Molecular Alterations Caused by Alcohol Consumption in the UK Biobank: A Mendelian Randomisation Study.Semantic proximity Read ↗

Assessment of causality between serum gamma-glutamyltransferase and type 2 diabetes mellitus using publicly available data: a Mendelian randomization study.Semantic proximity Read ↗

To explore association between gamma-glutamyl transferase and type 2 diabetes using a real-world study and mendelian randomization analysisSemantic proximity Read ↗

Association between alcohol consumption and Alzheimer’s disease: A Mendelian randomization StudySemantic proximity Read ↗

Exploring causal associations of alcohol with cardiovascular and metabolic risk factors in a Chinese population using Mendelian randomization analysis.Semantic proximity Read ↗

The effect of metabolism-related lifestyle and clinical risk factors on digestive system cancers in East Asian populations: a two-sample Mendelian randomization analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.