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Article

Genetic Causal Relationship Between Alanine Aminotransferase Levels and Risk of Gestational Diabetes Mellitus: Mendelian Randomization Analysis Based on Two Samples.

Twin research and human genetics : the official journal of the International Society for Twin Studies - 1 Apr 2024

Yin Lihua, Hu Yifang, Hu Xiaoxia, Huang Xiaolei, Chen Yingyuan, Zhang Yisheng

Abstract excerpt

Gestational diabetes mellitus (GDM) is a frequent complication of pregnancy. The specific mechanisms underlying GDM have not yet been fully elucidated. Contemporary research indicates a potential association between liver enzyme irregularities and an increased risk of metabolic disorders, including diabetes. The alanine aminotransferase (ALT) level is recognized as a sensitive marker of liver injury. An increase...

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PMID: 38634508
DOI: 10.1017/thg.2024.16

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