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Article

Identification of Putative Causal Relationships Between Type 2 Diabetes and Blood-Based Biomarkers in East Asians by Mendelian Randomization.

American journal of epidemiology - 20 Oct 2022

Zhang Haoyang, Xiu Xuehao, Yang Yuedong, Yang Yuanhao, Zhao Huiying

Abstract excerpt

Observational studies have revealed phenotypic associations between type 2 diabetes (T2D) and many biomarkers. However, causality between these conditions in East Asians is unclear. We leveraged genome-wide association study (GWAS) summary statistics on T2D (n = 77,418 cases; n = 356,122 controls) from the Asian Genetic Epidemiology Network (sample recruited during 2001-2011) and GWAS summary statistics on 42...

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PMID: 35801869
DOI: 10.1093/aje/kwac118

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