Article
Race/Ethnicity and the Pharmacogenetics of Reported Suicidality With Efavirenz Among Clinical Trials Participants.
The Journal of infectious diseases - 1 Sept 2017
Mollan Katie R, Tierney Camlin, Hellwege Jacklyn N, Eron Joseph J, Hudgens Michael G, Gulick Roy M, Haubrich Richard, Sax Paul E, Campbell Thomas B, Daar Eric S, Robertson Kevin R, Ventura Diana, Ma Qing, Edwards Digna R Velez, Haas David W
Abstract excerpt
Background: We examined associations between suicidality and genotypes that predict plasma efavirenz exposure among AIDS Clinical Trials Group study participants in the United States. Methods: Four clinical trials randomly assigned treatment-naive participants to efavirenz-containing regimens; suicidality was defined as reported suicidal ideation or attempted or completed suicide. Genotypes that predict plasma...
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