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Article

The impact of tumor profiling approaches and genomic data strategies for cancer precision medicine

26 Jul 2016

Abstract excerpt

BACKGROUND: The diversity of clinical tumor profiling approaches (small panels to whole exomes with matched or unmatched germline analysis) may engender uncertainty about their benefits and liabilities, particularly in light of reported germline false positives in tumor-only profiling and use of global mutational and/or neoantigen data. The goal of this study was to determine the impact of genomic analysis...

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PMID: 27460824
DOI: 10.1186/s13073-016-0333-9

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