Article
MSTNDel73C Mutation Modulates Glycerophospholipid Metabolism During Osteogenic Differentiation of Sheep BMSCs.
Cells - 23 Jun 2026
Wang Luyu, Liu Yanhao, Wu Aowu, Cao Jingchao, Zhao Yiping, Wang Yibo, Ning Wenxi, Lian Zhengxing, Yu Kun
Abstract excerpt
Myostatin (MSTN) is a well-established negative regulator of skeletal muscle growth; however, its role in bone metabolism and osteogenic differentiation remains incompletely understood. In this study, untargeted and targeted metabolomic analyses were performed to investigate the metabolic effects of the MSTNDel73C mutation during osteogenic differentiation of sheep bone marrow mesenchymal stem cells (BMSCs)....
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