Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Herpes simplex encephalitis is linked with selective mitochondrial damage; a post-mortem and in vitro study

25 Jul 2016

Abstract excerpt

Herpes simplex virus type-1 (HSV-1) encephalitis (HSE) is the most commonly diagnosed cause of viral encephalitis in western countries. Despite antiviral treatment, HSE remains a devastating disease with high morbidity and mortality. Improved understanding of pathogenesis may lead to more effective therapies. Mitochondrial damage has been reported during HSV infection in vitro. However, whether it occurs in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to Herpesvirus Infections and Treatments
Share to RNA regulation and disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27457581
DOI: 10.1007/s00401-016-1597-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Herpes simplex encephalitis is linked with selective mitochondrial damage; a post-mortem and in vitro studyPMID 27457581Read ↗

Examination of the host response in brain tissue during herpes simplex virus encephalitisSemantic proximity Read ↗

Mitochondrial DNA Instability and Neuroinflammation: Connecting the Dots Between Base Excision Repair and Neurodegenerative DiseaseSemantic proximity Read ↗

Altered mitochondrial dynamics as a consequence of Venezuelan Equine encephalitis virus infectionSemantic proximity Read ↗

Loss of mtDNA activates astrocytes and leads to spongiotic encephalopathy.Semantic proximity Read ↗

Mutations Causative of CPEO Differentially Engage Innate Immunity SensorsSemantic proximity Read ↗

Stem cell derived astrocytes with <i>POLG</i> mutations and mitochondrial dysfunction including abnormal NAD+ metabolism is toxic for neuronsSemantic proximity Read ↗

Hypoxic stress is an early pathogenic event in human VCP-mutant ALS astrocytes.Semantic proximity Read ↗

A novel mitochondrial DNA mutation in COX1 leads to strokes, seizures, and lactic acidosis.Semantic proximity Read ↗

Fulminant Hemorrhagic Necrosis in Herpes Simplex Virus Encephalitis: A Case Report and Literature ReviewSemantic proximity Read ↗

Encephalitic Alphavirus Infection Induces PARP-1 Hyperactivation Mediated Energy Collapse in Motor NeuronsSemantic proximity Read ↗

Mitochondrial DNA Heteroplasmy as an Informational Reservoir Dynamically Linked to Metabolic and Immunological Processes Associated with COVID-19 Neurological DisordersSemantic proximity Read ↗

HCMV infection depends on EGLN1-mediated mitochondrial activation to increase dNTP pools for viral DNA replicationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.