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Article

Diguanylate cyclase activity of the Mycobacterium leprae T cell antigen ML1419c.

Microbiology (Reading, England) - 1 Sept 2016

Rotcheewaphan Suwatchareeporn, Belisle John T, Webb Kristofor J, Kim Hee-Jin, Spencer John S, Borlee Bradley R

Abstract excerpt

The second messenger, bis-(3',5')-cyclic dimeric guanosine monophosphate (cyclic di-GMP), is involved in the control of multiple bacterial phenotypes, including those that impact host-pathogen interactions. Bioinformatics analyses predicted that Mycobacterium leprae, an obligate intracellular bacterium and the causative agent of leprosy, encodes three active diguanylate cyclases. In contrast, the related pathogen...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27450520
DOI: 10.1099/mic.0.000339
PMCID: PMC5772806

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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