Article
TLR4 and DC-SIGN receptors recognized Mycobacterium scrofulaceum promoting semi-activated phenotype on bone marrow dendritic cells.
Tuberculosis (Edinburgh, Scotland) - 1 Jul 2016
Cruz-Aguilar Marisa, Castillo-Rodal Antonia I, Schcolnik-Cabrera Alejandro, Bonifaz Laura C, Molina Gabriela, López-Vidal Yolanda
Abstract excerpt
Nontuberculous mycobacteria (NTM) are recognized as emerging pathogens and their immune regulatory mechanisms are not well described yet. From them, Mycobacterium avium is known to be a weak activator of dendritic cells (DCs) that impairs the response induced by BCG vaccine. However, whether other NTM such as Mycobacterium scrofulaceum may modulate the activation of DCs, has not been extensively studied. Here, we...
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