Article
Deciphering the molecular bases of<i>Mycobacterium tuberculosis</i>binding to the lectin DC-SIGN reveals an underestimated complexity
6 Dec 2005
Abstract excerpt
Interactions between dendritic cells and Mycobacterium tuberculosis, the aetiological agent of tuberculosis in humans, are thought to be central to anti-mycobacterial immunity. We have previously shown that M. tuberculosis binds to human monocyte-derived dendritic cells mostly through the C-type lectin DC-SIGN (dendritic-cell-specific intercellular molecule-3-grabbing non-integrin)/CD209, and we have suggested...
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