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Article

Gene mutations and actionable genetic lesions in mantle cell lymphoma.

Oncotarget - 6 Sept 2016

Ahmed Makhdum, Zhang Leo, Nomie Krystle, Lam Laura, Wang Michael

Abstract excerpt

Mutations and epigenetic alterations are key events in transforming normal cells to cancer cells. Mantle cell lymphoma (MCL), a non-Hodgkin's lymphoma of the B-cell, is an aggressive malignancy with poor prognosis especially for those patients who are resistant to the frontline drugs. There is a great need to describe the molecular basis and mechanism of drug resistance in MCL to develop new strategies for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins c-bcl-2

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Source

Open in PubMed Open full text

Identifiers

PMID: 27449094
DOI: 10.18632/oncotarget.10716
PMCID: PMC5295458

Genes

ATM
CCND1
NOTCH1
TRAF2

Provenance

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