Article
Novel agents for mantle cell lymphoma: molecular rational and clinical data.
Expert opinion on investigational drugs - 1 Jun 2020
Sarkozy Clémentine, Ribrag Vincent
Abstract excerpt
INTRODUCTION: Mantle cell lymphoma (MCL) is an aggressive B cell non-Hodgkin lymphoma (NHL) that is characterized by the translocation t(11;14)(q13;q32) and a poor response to rituximab-anthracycline-based chemotherapy. Intensive regimens offer durable response, but a subgroup of MCL patients will not be eligible for those regimens and hence are candidates for less toxic, novel therapies based on a more tailored...
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