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Article

Telomere protein RAP1 levels are affected by cellular aging and oxidative stress

28 Jun 2016

Abstract excerpt

Telomeres are important for maintaining the integrity of the genome through the action of the shelterin complex. Previous studies indicted that the length of the telomere did not have an effect on the amount of the shelterin subunits; however, those experiments were performed using immortalized cells with stable telomere lengths. The interest of the present study was to observe how decreasing telomere lengths...

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Share to DNA Repair Mechanisms
Share to Genetics, Aging, and Longevity in Model Organisms
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Identifiers

PMID: 27446538
DOI: 10.3892/br.2016.707

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