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Synchronous Metastatic Clear-Cell Renal Cell Carcinoma: A Distinct Morphologic, Immunohistochemical, and Molecular Phenotype.

Clinical genitourinary cancer - 1 Feb 2017

Kammerer-Jacquet Solene-Florence, Brunot Angelique, Pladys Adelaide, Bouzille Guillaume, Dagher Julien, Medane Sarah, Peyronnet Benoit, Mathieu Romain, Verhoest Gregory, Bensalah Karim, Edeline Julien, Laguerre Brigitte, Lespagnol Alexandra, Mosser Jean, Dugay Frederic, Belaud-Rotureau Marc-Antoine, Rioux-Leclercq Nathalie

Abstract excerpt

INTRODUCTION: Clear cell renal cell carcinomas (ccRCCs) are highly metastatic tumors with metastases detected at diagnosis (synchronous) or during follow-up (metachronous). To date, there have been no reports comparing primary ccRCC of patients with synchronous and metachronous metastases, who are different in terms of prognosis. Determining whether there is a phenotypic difference between these 2 groups could...

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PMID: 27444986
DOI: 10.1016/j.clgc.2016.06.007

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VHL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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