Article
Heterogeneous drug target expression as possible basis for different clinical and radiological response to the treatment of primary and metastatic renal cell carcinoma: suggestions from bench to bedside.
Cancer metastasis reviews - 1 Mar 2014
Santoni Matteo, Santini Daniele, Massari Francesco, Conti Alessandro, Iacovelli Roberto, Burattini Luciano, Tortora Giampaolo, Falconi Massimo, Montironi Rodolfo, Cascinu Stefano
Abstract excerpt
Metastatic disease occurs in a significant percentage of patients with renal cell carcinoma (RCC) and is usually associated with an overall poor prognosis. However, not all of the sites of metastases seem to have the same prognostic significance in patients receiving targeted agents. Indeed, patients with lung-only metastases seem to present a better survival than patients with other sites, whereas liver and bone...
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