Changes in selective pressures associated with human population expansion may explain metabolic and immune related pathways enriched for signatures of positive selection.

Abstract excerpt

BACKGROUND: The study of local adaptation processes is a very important research topic in the field of population genomics. There is a particular interest in the study of human populations because they underwent a process of rapid spatial expansion and faced important environmental changes that translated into changes in selective pressures. New mutations may have been selected for in the new environment and...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Adaptation, Biological
• Share to Biological Evolution