Article
Genome-wide landscape establishes novel association signals for metabolic traits in the Arab population.
Human genetics - 1 Mar 2021
Hebbar Prashantha, Abubaker Jehad Ahmed, Abu-Farha Mohamed, Alsmadi Osama, Elkum Naser, Alkayal Fadi, John Sumi Elsa, Channanath Arshad, Iqbal Rasheeba, Pitkaniemi Janne, Tuomilehto Jaakko, Sladek Robert, Al-Mulla Fahd, Thanaraj Thangavel Alphonse
Abstract excerpt
While the Arabian population has a high prevalence of metabolic disorders, it has not been included in global studies that identify genetic risk loci for metabolic traits. Determining the transferability of such largely Euro-centric established risk loci is essential to transfer the research tools/resources, and drug targets generated by global studies to a broad range of ethnic populations. Further,...
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