Article
Association study of TLR-9 polymorphisms and systemic lupus erythematosus in northern Chinese Han population.
Gene - 1 Jan 2014
Zhang Jihui, Zhu Qigui, Meng Fanhua, Lei Hongwei, Zhao Yinhuan
Abstract excerpt
BACKGROUND: Systemic lupus erythematosus (SLE) is an autoimmune disease, with multiple genetic and environmental factors involving in its etiology. The toll-like receptor 9 (TLR9) gene has been reported to have important roles in the development and progression of SLE. We performed a case-control study to investigate the effects of 4 SNPs in the TLR9 gene in the development of SLE in Northern Chinese population....
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