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Article

Alcohol Suppresses Tonic GABAA Receptor Currents in Cerebellar Granule Cells in the Prairie Vole: A Neural Signature of High-Alcohol-Consuming Genotypes.

Alcoholism, clinical and experimental research - 1 Aug 2016

Kaplan Joshua S, Mohr Claudia, Hostetler Caroline M, Ryabinin Andrey E, Finn Deborah A, Rossi David J

Abstract excerpt

BACKGROUND: Evidence indicates that the cerebellum plays a role in genetic predilection to excessive alcohol (ethanol [EtOH]) consumption in rodents and humans, but the molecular mechanisms mediating such predilection are not understood. We recently determined that EtOH has opposite actions (enhancement or suppression) on tonic GABAA receptor (GABAA R) currents in cerebellar granule cells (GCs) in low- and...

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Identifiers

PMID: 27426857
DOI: 10.1111/acer.13136
PMCID: PMC4961518

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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