Article
Association of single nucleotide polymorphisms in Pre-miR-27a, Pre-miR-196a2, Pre-miR-423, miR-608 and Pre-miR-618 with breast cancer susceptibility in a South American population.
BMC genetics - 15 Jul 2016
Morales Sebastián, Gulppi Felipe, Gonzalez-Hormazabal Patricio, Fernandez-Ramires Ricardo, Bravo Teresa, Reyes José Miguel, Gomez Fernando, Waugh Enrique, Jara Lilian
Abstract excerpt
BACKGROUND: MicroRNAs (miRNAs) are a novel class of endogenous, non-coding, single-stranded RNAs capable of regulating gene expression by suppressing translation or degrading mRNAs. Single nucleotide polymorphisms (SNP) can alter miRNA expression, resulting in diverse functional consequences. Previous studies have examined the association of miRNA SNPs with breast cancer (BC) susceptibility. The contribution of...
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