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Assembling of the Mycobacterium tuberculosis Cell Wall Core

15 Jul 2016

Abstract excerpt

The unique cell wall of mycobacteria is essential to their viability and the target of many clinically used anti-tuberculosis drugs and inhibitors under development. Despite intensive efforts to identify the ligase(s) responsible for the covalent attachment of the two major heteropolysaccharides of the mycobacterial cell wall, arabinogalactan (AG) and peptidoglycan (PG), the enzyme or enzymes responsible have...

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PMID: 27417139
DOI: 10.1074/jbc.m116.739227

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