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Revisiting Anti-tuberculosis Therapeutic Strategies That Target the Peptidoglycan Structure and Synthesis

11 Feb 2019

Abstract excerpt

One of the leading causes of infectious diseases death worldwide is tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb). The biosynthesis of the mycobacterial cell wall (CW) is an area of significant research interest, as several of the antibiotics used to treat TB target biosynthesis pathways of essential CW components. The main feature of the mycobacterial CW is an intricate structure, the...

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PMID: 30804921
DOI: 10.3389/fmicb.2019.00190

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