Article
-759 C/T polymorphism of 5-HT2C receptor gene and early phase weight gain associated with antipsychotic drug treatment.
Progress in neuro-psychopharmacology & biological psychiatry - 13 Apr 2007
Ryu Seunghyong, Cho Eun Young, Park Taesung, Oh Sohee, Jang Won-Seok, Kim Shin-Kyum, Lee Dongsoo, Hong Kyung Sue
Abstract excerpt
5-HT2C receptor gene is viewed as an important candidate gene in pharmacogenetic studies of antipsychotic drug-induced weight gain. However, inconsistent results have been obtained in different populations. We investigated the association between the -759C/T polymorphism of the 5-HT2C receptor gene with early phase (after 4 weeks of treatment) weight gain induced by antipsychotic treatment in Korean schizophrenia...
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