Article
Tracking Cancer Genetic Evolution using OncoTrack.
Scientific reports - 14 Jul 2016
Talukder Asoke K, Agarwal Mahima, Buetow Kenneth H, Denèfle Patrice P
Abstract excerpt
It is difficult for existing methods to quantify, and track the constant evolution of cancers due to high heterogeneity of mutations. However, structural variations associated with nucleotide number changes show repeatable patterns in localized regions of the genome. Here we introduce SPKMG, which generalizes nucleotide number based properties of genes, in statistical terms, at the genome-wide scale. It is...
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