Article
Germline genetic variation in JAK2 as a prognostic marker in castration-resistant prostate cancer.
BJU international - 1 Mar 2017
Zhang Ben Y, Riska Shaun M, Mahoney Douglas W, Costello Brian A, Kohli Rhea, Quevedo Jorge F, Cerhan James R, Kohli Manish
Abstract excerpt
OBJECTIVES: To evaluate the prognostic significance of germline variation in candidate genes in patients with castration-resistant prostate cancer (CRPC). METHODS: Germline DNA was extracted from peripheral blood mononuclear cells of patients with CRPC enrolled in a clinically annotated registry. Fourteen candidate genes implicated in either initiation or progression of prostate cancer were tagged using single...
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