Article
Genetic profiling of hormone-sensitive and castration-resistant prostate cancers and identification of genetic mutations prone to castration-resistant prostate cancer.
Prostate cancer and prostatic diseases - 1 Mar 2023
Wang Ze, Yan Xuzhi, Tang Peng, Tang Tang, Wang Yapeng, Peng Song, Wang Shuo, Lan Weihua, Wang Luofu, Zhang Yao, Zhang Jun, Li Ke, Shu Zehua, Xu Jing, Qin Jun, Zhang Dianzheng, Jiang Jun, Liu Qiuli
Abstract excerpt
BACKGROUND: Genetic profiling of patients with prostate cancer could potentially identify mutations prone to castration-resistant prostate cancer (CRPC). Here, we aimed to identify the differences in genetic profiles of patients with hormone-sensitive prostate cancer (HSPC) and CRPC and stratify HSPC patients to identify mutations associated with CRPC progression. METHODS: A total of 103 samples were collected,...
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