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Article

Association of genetic variation of the six gene prognostic model for castration-resistant prostate cancer with survival.

The Prostate - 1 Jan 2019

Xie Wanling, Stopsack Konrad H, Drouin Sarah J, Fu Henry, Pomerantz Mark M, Mucci Lorelei A, Lee Gwo-Shu M, Kantoff Philip W

Abstract excerpt

BACKGROUND: We previously identified a blood RNA transcript-based model consisting of six immune or inflammatory response genes (ABL2, SEMA4D, ITGAL, C1QA, TIMP1, and CDKN1A) that was prognostic for survival in cohorts of men with castration-resistant prostate cancer (CRPC). We investigated whether inherited variation in these six genes was associated with overall survival (OS) in men with CRPC. METHODS: The test...

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Identifiers

PMID: 30141208
DOI: 10.1002/pros.23712
PMCID: PMC6476182

Genes

ABL2
ITGAL
TIMP1

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