GATA4 variant interaction with brain limbic structure and relapse risk: A voxel-based morphometry study.

doi:10.1016/j.euroneuro.2016.06.011

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

GATA4 variant interaction with brain limbic structure and relapse risk: A voxel-based morphometry study.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Sept 2016

Zois Evangelos, Vollstädt-Klein Sabine, Hoffmann Sabine, Reinhard Iris, Bach Patrick, Charlet Katrin, Beck Anne, Treutlein Jens, Frank Josef, Jorde Anne, Kirsch Martina, Degenhardt Franziska, Walter Henrik, Heinz Andreas, Kiefer Falk

Abstract excerpt

Atrial natriuretic peptide (ANP) receptors are highly expressed in the amygdala, caudate and hypothalamus. GATA4 gene encodes a transcription factor of ANP associated with the pathophysiology of alcohol dependence. We have previously demonstrated that the GATA4 single nucleotide polymorphism (SNP) rs13273672 revealed stronger alcohol-specific amygdala activation associated with lowered relapse risk to heavy...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcoholism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GATA4 Transcription Factor

Share to Gray Matter

Share to Image Processing, Computer-Assisted

Share to Limbic System

Share to Organ Size

Share to Proportional Hazards Models

Share to Recurrence

Source

Open in PubMed

Identifiers

PMID: 27397865
DOI: 10.1016/j.euroneuro.2016.06.011

Genes

GATA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

GATA4 variant interaction with brain limbic structure and relapse risk: A voxel-based morphometry study.PMID 27397865Read ↗

Genetic variation in the atrial natriuretic peptide transcription factor GATA4 modulates amygdala responsiveness in alcohol dependence.Semantic proximity Read ↗

Involvement of the atrial natriuretic peptide transcription factor GATA4 in alcohol dependence, relapse risk and treatment response to acamprosate.Semantic proximity Read ↗

Association Analysis Between Genetic Variation in GATA Binding Protein 4 (GATA4) and Alcohol Use Disorder.Semantic proximity Read ↗

Association of the alcohol dehydrogenase gene polymorphism rs1789891 with gray matter brain volume, alcohol consumption, alcohol craving and relapse risk.Semantic proximity Read ↗

Genetic variation within GRIN2B in adolescents with alcohol use disorder may be associated with larger left posterior cingulate cortex volume.Semantic proximity Read ↗

Shared genetic factors influence amygdala volumes and risk for alcoholism.Semantic proximity Read ↗

Association of GATA4 sequence variation with alcohol dependence.Semantic proximity Read ↗

Serotonin transporter gene methylation is associated with hippocampal gray matter volume.Semantic proximity Read ↗

Human amygdala volume is predicted by common DNA variation in the stathmin and serotonin transporter genes.Semantic proximity Read ↗

Common genetic variation near MC4R has a sex-specific impact on human brain structure and eating behavior.Semantic proximity Read ↗

MAO A VNTR polymorphism and amygdala volume in healthy subjects.Semantic proximity Read ↗

Functional (GT)n polymorphisms in promoter region of N-methyl-d-aspartate receptor 2A subunit (GRIN2A) gene affect hippocampal and amygdala volumes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.