Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

KIT genetic alterations in breast cancer.

Journal of clinical pathology - 14 Dec 2023

Vahdatinia Mahsa, Derakhshan Fatemeh, Da Cruz Paula Arnaud, Dopeso Higinio, Marra Antonio, Gazzo Andrea M, Brown David, Selenica Pier, Ross Dara S, Razavi Pedram, Zhang Hong, Weigelt Britta, Wen Hannah Y, Brogi Edi, Reis-Filho Jorge S, Pareja Fresia

Abstract excerpt

AIMS: Activating somatic mutations or gene amplification of KIT result in constitutive activation of its receptor tyrosine kinase, which is targetable in various solid tumours. Here, we sought to investigate the presence of KIT genetic alterations in breast cancer (BC) and characterise the histological and genomic features of these tumours. METHODS: A retrospective analysis of 5,575 BCs previously subjected to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genomics
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Breast Neoplasms

Share to Gene Amplification

Source

Open in PubMed Open full text

Identifiers

PMID: 36323507
DOI: 10.1136/jcp-2022-208611
PMCID: PMC10151428

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

KIT genetic alterations in breast cancer.PMID 36323507Read ↗

KIT Oncogenic Mutations: Biologic Insights, Therapeutic Advances, and Future Directions.Semantic proximity Read ↗

Somatic gene mutation analysis of triple negative breast cancers.Semantic proximity Read ↗

Molecular Pathology of Breast Tumors: Diagnostic and Actionable Genetic Alterations.Semantic proximity Read ↗

Molecular Pathology of Breast Tumors: Diagnostic and Actionable Genetic Alterations.Semantic proximity Read ↗

KIT gene mutation analysis in solid tumours: biology, clincial applications and trends in diagnostic reporting.Semantic proximity Read ↗

c-Kit Receptors as a Therapeutic Target in Cancer: Current InsightsSemantic proximity Read ↗

Molecular alterations and prognosis of breast cancer with cutaneous metastasis.Semantic proximity Read ↗

Molecular Testing in Breast Cancer: A Guide to Current Practices.Semantic proximity Read ↗

Analysis of MET genetic aberrations in patients with breast cancer at MD Anderson Phase I unit.Semantic proximity Read ↗

Kit Mutations: New Insights and Diagnostic Value.Semantic proximity Read ↗

Morphology and genomic hallmarks of breast tumours developed by ATM deleterious variant carriers.Semantic proximity Read ↗

Nonamplification ERBB2 genomic alterations in 5605 cases of recurrent and metastatic breast cancer: An emerging opportunity for anti-HER2 targeted therapies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.