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Article

Polymorphisms in DNA repair genes XRCC1 and OGG1 lead to the progression of rheumatoid arthritis in Pakistani patients.

Pakistan journal of pharmaceutical sciences - 1 Jul 2016

Qadir Mirza Muhammad Fahd, Bhatti Attya, Khurshid Rabia, Ashraf Muhammad Usman, Anjum Sidrah, John Peter

Abstract excerpt

This study points at the elucidation of a possible association of Rheumatoid arthritis (RA) with Ser326Cys in OGG1 Arg194Trp and Arg399Gln polymorphisms of XRCC1 using a sample size of 100 patients and 100 controls from a Pakistani population. This association was determined using Random Fragment Length Polymorphism Analysis as well as the DAS scoring system. In RA, oxidative damage due to free radical production...

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Topics

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Share to Arthritis, Rheumatoid
Share to Disease Progression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genetic Predisposition to Disease

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Share to Polymorphism, Single Nucleotide

Share to X-ray Repair Cross Complementing Protein 1

Source

Identifiers

PMID: 27393451

Genes

XRCC1
OGG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Polymorphisms in DNA repair genes XRCC1 and OGG1 lead to the progression of rheumatoid arthritis in Pakistani patients.PMID 27393451Read ↗

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