Article
Association of the 399Arg/Gln XRCC1, the 194 Arg/Trp XRCC1, the 326Ser/Cys OGG1, and the 324Gln/His MUTYH gene polymorphisms with clinical parameters and the risk for development of primary open-angle glaucoma.
Mutation research - 30 Apr 2013
Szaflik Jacek P, Cuchra Magda, Przybylowska-Sygut Karolina, Dziki Lukasz, Kurowska Anna K, Gacek Mira, Drzewoski Jozef, Szaflik Jerzy, Majsterek Ireneusz
Abstract excerpt
BACKGROUND: Numerous data have shown that progressive loss of human trabecular meshwork (TM) cells may be connected with oxidative stress. This hypothesis may suggest an association of base excision repair with the risk of primary open angle glaucoma development. PURPOSE: The aim of this study was to evaluate the role of the 399Arg/Gln XRCC1, the 194 Arg/Trp XRCC1, the 326SerCys OGG1, and the 324Gln/His MUTYH...
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