Frequency and outcome of pediatric acute lymphoblastic leukemia with <i>ZNF384</i> gene rearrangements including a novel translocation resulting in an <i>ARID1B/ZNF384</i> gene fusion

Abstract excerpt

BACKGROUND: ZNF384 gene rearrangements with multiple partner genes are recurrent in acute leukemia and are most often associated with a precursor B cell immunophenotype. The overall incidence of this genetic category of leukemia is uncertain. PROCEDURE: Patients with ZNF384 gene rearrangements from a cohort of 240 precursor B cell acute lymphoblastic leukemia (ALL) pediatric patients over a 3.5-year time period...

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