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Article

Serine-arginine protein kinase 1 promotes a cancer stem cell-like phenotype through activation of Wnt/β-catenin signalling in NSCLC.

The Journal of pathology - 1 Oct 2016

Gong Liyun, Song Junwei, Lin Xi, Wei Fakai, Zhang Cuicui, Wang Zimei, Zhu Jinrong, Wu Shu, Chen Yu, Liang Jin, Fu XiaoYuan, Lu Junqiang, Zhou Chunhui, Song Libing

Abstract excerpt

Cancer stem cells (CSCs) are commonly associated with cancer recurrence and metastasis that occurs in up to 30-55% of non-small-cell lung carcinoma (NSCLC) patients. Herein, we showed that serine-arginine protein kinase 1 (SRPK1) was highly expressed at both the mRNA and the protein levels in human NCSLC. SRPK1 was associated with the clinical features of human NSCLC, including clinical stage (p < 0.001) and T (p...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27391422
DOI: 10.1002/path.4767

Genes

SRPK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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