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Article

Role of Interleukin 36γ in Host Defense Against Tuberculosis

18 Apr 2016

Abstract excerpt

Tuberculosis remains a major killer worldwide, not the least because of our incomplete knowledge of protective and pathogenic immune mechanism. The roles of the interleukin 1 (IL-1) and interleukin 18 pathways in host defense are well established, as are their regulation through the inflammasome complex. In contrast, the regulation of interleukin 36γ (IL-36γ), a recently described member of the IL-1 family, and...

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PMID: 27389350
DOI: 10.1093/infdis/jiw152

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