Article

Undetected Multidrug-Resistant Tuberculosis Amplified by First-line Therapy in Mixed Infection

2013-07-01

Abstract excerpt

Infections with >1 Mycobacterium tuberculosis strain(s) are underrecognized. We show, in vitro and in vivo, how first-line treatment conferred a competitive growth advantage to amplify a multidrug-resistant M. tuberculosis strain in a patient with mixed infection. Diagnostic techniques that identify mixed tubercle bacilli populations are needed to curb the spread of multidrug resistance.

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Literature Corpus work: ce2627fb-81bb-5d95-ac62-d274b489d8b2
DOI: 10.3201/eid1907.130313

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