Back to search

Article

Culture filtrate selectively promotes <i>Mycobacterium tuberculosis</i> growth from extremely low density inocula: implications for quantifying differentially culturable phenotypes

2025-10-15

Abstract excerpt

Differentially culturable (DC) Mycobacterium tuberculosis ( Mtb ) phenotypes reduce the sensitivity of sputum culture and may be associated with adverse treatment outcomes among tuberculosis patients. Accurately quantifying DC Mtb remains an important research objective, with current approaches tending to combine Most Probable Number (MPN) assays and culture filtrate (CF) supplementation. These assume that grow...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
b08515a0-6ada-5201-9773-54e7fc4849ac
DOI
10.1101/2025.10.15.682508
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Culture filtrate selectively promotes <i>Mycobacterium tuberculosis</i> growth from extremely low density inocula: implications for quantifying differentially culturable phenotypesDOI 10.1101/2025.10.15.682508
Beyond culturability: VBNC-like and differentially culturable Mycobacterium tuberculosis challenge growth-based interpretations of bacterial viability.Semantic proximity
Detection and Quantification of Differentially Culturable Tubercle Bacteria in Sputum from Patients with TuberculosisSemantic proximity
Clinically encountered growth phenotypes of tuberculosis-causing bacilli and their in vitro study: A review.Semantic proximity
Detection of differentially culturable tubercle bacteria in sputum using mycobacterial culture filtratesSemantic proximity
Flow cytometry method for absolute counting and single-cell phenotyping of mycobacteriaSemantic proximity
Drug-induced differential culturability in diverse strains of <i>Mycobacterium tuberculosis</i>Semantic proximity
Exposure to nitric oxide drives transition to differential culturability in <i>Mycobacterium tuberculosis</i>Semantic proximity
High-throughput cytological profiling uncovers genotype-phenotype associations in Mycobacterium tuberculosis clinical isolates.Semantic proximity
Mycobacterial Cultures Contain Cell Size and Density Specific Sub-populations of Cells with Significant Differential Susceptibility to Antibiotics, Oxidative and Nitrite StressSemantic proximity
Aerosolization of viable<i>Mycobacterium tuberculosis</i>bacilli by tuberculosis clinic attendees independent of sputum-GeneXpert statusSemantic proximity
Characterization of Drug-Resistant Lipid-Dependent Differentially Detectable Mycobacterium tuberculosisSemantic proximity
Elucidating population-wide mycobacterial replication dynamics at the single-cell levelSemantic proximity
Select a neighboring publication to make it the new centre.