Article
Genetic variants of neurotransmitter-related genes and miRNAs in Egyptian autistic patients.
TheScientificWorldJournal - 1 Jan 2013
Salem Ahmed M, Ismail Samira, Zarouk Waheba A, Abdul Baky Olwya, Sayed Ahmed A, Abd El-Hamid Sawsan, Salem Sohair
Abstract excerpt
Autism is a neurodevelopmental disorder with indisputable evidence for a genetic component. This work studied the association of autism with genetic variations in neurotransmitter-related genes, including MAOA uVNTR, MAOB rs1799836, and DRD2 TaqI A in 53 autistic patients and 30 healthy individuals. The study also analyzed sequence variations of miR-431 and miR-21. MAOA uVNTR was genotyped by PCR, MAOB and DRD2...
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