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The Roles of Autophagy and Senescence in the Tumor Cell Response to Radiation

30 Jun 2020

Abstract excerpt

Radiation is a critical pillar in cancer therapeutics, exerting its anti-tumor DNA-damaging effects through various direct and indirect mechanisms. Radiation has served as an effective mode of treatment for a number of cancer types, providing both curative and palliative treatment; however, resistance to therapy persists as a fundamental limitation. While cancer cell death is the ideal outcome of any anti-tumor...

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PMID: 32845995
DOI: 10.1667/rade-20-00009

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