Article
Genome-wide association study of behavioral, physiological and gene expression traits in outbred CFW mice.
Nature genetics - 1 Aug 2016
Parker Clarissa C, Gopalakrishnan Shyam, Carbonetto Peter, Gonzales Natalia M, Leung Emily, Park Yeonhee J, Aryee Emmanuel, Davis Joe, Blizard David A, Ackert-Bicknell Cheryl L, Lionikas Arimantas, Pritchard Jonathan K, Palmer Abraham A
Abstract excerpt
Although mice are the most widely used mammalian model organism, genetic studies have suffered from limited mapping resolution due to extensive linkage disequilibrium (LD) that is characteristic of crosses among inbred strains. Carworth Farms White (CFW) mice are a commercially available outbred mouse population that exhibit rapid LD decay in comparison to other available mouse populations. We performed a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
