Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Relation of genomic variants for Alzheimer disease dementia to common neuropathologies.

Neurology - 2 Aug 2016

Farfel Jose M, Yu Lei, Buchman Aron S, Schneider Julie A, De Jager Philip L, Bennett David A

Abstract excerpt

OBJECTIVE: To investigate the associations of previously reported Alzheimer disease (AD) dementia genomic variants with common neuropathologies. METHODS: This is a postmortem study including 1,017 autopsied participants from 2 clinicopathologic cohorts. Analyses focused on 22 genomic variants associated with AD dementia in large-scale case-control genome-wide association study (GWAS) meta-analyses. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoproteins E
Share to Cerebral Infarction
Share to Hippocampus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lewy Bodies

Share to Logistic Models

Share to Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases

Share to Receptors, Complement 3b

Share to Zinc Fingers

Source

Open in PubMed Open full text

Identifiers

PMID: 27371493
DOI: 10.1212/WNL.0000000000002909
PMCID: PMC4970661

Genes

APOE
FERMT2
ZCWPW1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Relation of genomic variants for Alzheimer disease dementia to common neuropathologies.PMID 27371493Read ↗

Multiple gene variants linked to Alzheimer's-type clinical dementia via GWAS are also associated with non-Alzheimer's neuropathologic entitiesSemantic proximity Read ↗

Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.Semantic proximity Read ↗

Genome wide association study meta-analysis of neuropathologic lesions of Alzheimer’s disease and related dementias in a multi-site autopsy cohortSemantic proximity Read ↗

Genome wide association study meta-analysis of neuropathologic lesions of Alzheimer's disease and related dementias in a multi-site autopsy cohort.Semantic proximity Read ↗

Contributions of rare and common variation to early-onset and atypical dementia riskSemantic proximity Read ↗

Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project.Semantic proximity Read ↗

Genetic risk factors for the posterior cortical atrophy variant of Alzheimer's disease.Semantic proximity Read ↗

Association of Rare Coding Mutations With Alzheimer Disease and Other Dementias Among Adults of European AncestrySemantic proximity Read ↗

Genome sequencing for early-onset or atypical dementia: high diagnostic yield and frequent observation of multiple contributory alleles.Semantic proximity Read ↗

Structural variants linked to Alzheimer’s Disease and other common age-related clinical and neuropathologic traitsSemantic proximity Read ↗

Hypothesis-based investigation of known AD risk variants reveals the genetic underpinnings of neuropathological lesions observed in Alzheimer's-type dementia.Semantic proximity Read ↗

Genome-Wide Association Study of Incident Dementia in a Community-Based Sample of Older Subjects.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.