Article
Deciphering the recent phylogenetic expansion of the originally deeply rooted Mycobacterium tuberculosis lineage 7.
BMC evolutionary biology - 30 Jun 2016
Yimer Solomon A, Namouchi Amine, Zegeye Ephrem Debebe, Holm-Hansen Carol, Norheim Gunnstein, Abebe Markos, Aseffa Abraham, Tønjum Tone
Abstract excerpt
BACKGROUND: A deeply rooted phylogenetic lineage of Mycobacterium tuberculosis (M. tuberculosis) termed lineage 7 was discovered in Ethiopia. Whole genome sequencing of 30 lineage 7 strains from patients in Ethiopia was performed. Intra-lineage genome variation was defined and unique characteristics identified with a focus on genes involved in DNA repair, recombination and replication (3R genes). RESULTS: More...
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